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The department provides a comprehensive histology service to the Royal Surrey County (RSCH), Frimley Park (FPH), Ashford & St.Peters Hospitals (ASPH) The Royal Berkshire Hospital (RBH) and Wexham Park Hospital (WPH) as well as to general practitioners, community and out-reach clinics in Central and Northwest Surrey areas. The service includes an extensive range of special techniques including immunohistochemistry, frozen sections, macrosectioning for complex lesions, lymph node recovery by lipid extraction, immunofluorescence, research and development facilities and an expanding molecular biology laboratory. The department provides assessment of melanoma sentinel lymph nodes for St George’s Hospital and SWSH Network.

Laboratories are based at Ashford & St.Peters Hospital, Frimley Park Hospital, The Royal Surrey County Hospital, The Royal Berkshire Hospital and Wexham Park Hospital the opening times are as follows:

Frimley Park Hospital: 08:30 - 17:00

The Royal Surrey County Hospital: 09:00 - 17:30

Ashford & St.Peters Hospital: 08:30 - 17:00

Wexham Park Hospital: 09:00 - 17:00

The Royal Berkshire Hospital: 09:00 - 17:00


The current unprecedented situation has resulted in the following aspects of three histopathology service being unavailable at RSCH, FPH and ASPH


·        Frozen Sections

·        Immunofluorescence (IMF)

·        OSNA


There are certain circumstances whereby an IMF would be considered should the patient have formally tested negative and the suspected disease state be life threatening. In these instances Dr Balamurugan must be contacted to approve the submission of such a specimen.


The department is working with subject matter experts to look to safely re-introduce all aspects of the histology service where possible. In the meantime, no specimen should be submitted to the department that is not immersed in formal saline/formalin.


James Woodland, Lead BMS, Histopathology (Surrey) 




All specimens should be directed to the Royal Surrey County Hospital, Frimley Park Hospital, Ashford & St. Peters, Wexham Park Hospital or the Royal Berkshire laboratories. Both specimen label and request form must be fully completed. The minimum requirements for completion of the form are:

  1. Name, sex, DOB and patient identifying numbers.
  2. Name of sender, ward, department or address of sender.
  3. Number, nature and site of specimens. Multiple specimens should be separately identified.
  4. Clinical details, including differential diagnosis (clinical information can strongly influence, if not determine, the histological diagnosis).
  5. Previous biopsy history, with laboratory numbers.
  6. The requesting doctor must indicate if the patient is private and sign the request form.

Please supply a contact telephone or pager number to facilitate discussion of the case by the Consultant Pathologist or laboratory staff.


Patient consent for histological diagnosis usually forms part of the surgical procedure consent, although with some POC evacuations this may not be the case. Only tissues with consent can be analysed by the department.

Acceptance and Rejection Criteria

Specimens received without the information detailed above will be rejected. The department will make contact with the requesting clinician in an attempt to complete any missing information.

Factors affecting examination of histological material

Formalin fixation (with the exception of IMF and Frozen section specimens) is critical for histological samples. Delays in fixation, or sub optimal fixation due to inadequate volumes of fixative, are known to potentially affect the results of histological examination. Thorough and relevant clinical information is also vital.

Protection of personal information

The laboratory takes all necessary measures to protect personal information supplied and observes all confidentiality and data protection guidance.


In the event of the service not meeting the users expectation, complaints can be made via email or telephone to the contact details given on the homepage. All complaints are taken very seriously and a full investigation will ensue.

Histopathology Referral Laboratory Details

Berkshire Laboratories:

Details of laboratories to which work is referred when required





The Bays, S Wharf Rd, Paddington, London, W2 1NY


Mindelsohn Way, Edgbaston, Birmingham, B15 2GW

Oxford - Nuffield

Windmill Rd, Headington, Oxford OX3 7HE

Oxford – John Radcliffe

Headley Way, Headington, Oxford OX3 9DU

Royal Marsden Hospital

203 Fulham Rd, Chelsea, London SW3 6JJ

Royal Brompton

Sydney St, Chelsea, London SW3 6NP

St Mary’s

Praed Street, London W2 1NY


Royal Hallamshire Hospital, Glossop Road, Sheffield

Source Bioscience

1 Orchard Place, Nottingham Business Park, Nottingham, NG8 6PX


Tremona Rd, Southampton SO16 6YD

University College London

Gower St, Bloomsbury, London WC1E 6BT


9 King's Head Yard, London SE1 1NA

Surrey Laboratories:

Whilst no routine testing is referred from the Surrey laboratories, there can be a requirement to seek expert opinion on complex unusual specimens. In these instances, the following institutes are engaged with. This list is not exhaustive, and the department reserves the right to seek any appropriate expert opinion in the interest of the patient.


Birmingham (Heartlands/Womans hospital)

University Hospitals Birmingham

Charing Cross Hospital, London (Imperial College Healthcare)

Dundee (NHS Tayside)

Exeter (Royal Devon)


John Radcliffe, Oxford (Oxford University Hospitals)

Institute of Opthalmology, London (UCL)

Newcastle Upon Tyne

St Thomas' Hospital, London (GSTS/ViaPath)

Nottingham University Hospital

RNOH, Stanmore

Royal Brompton, London

Royal Hallamshire (Sheffield Teaching Hospitals)

Royal Marsden

Royal Marsden

Liver Institute, King’s College London (GSTS/Viapath)

Southampton General Hospital

St George’s, London

St George’s, London

St James', Leeds (Leeds Teaching Hospital)

St James', Leeds (Leeds Teaching Hospital)

St Thomas' Hospital, London (GSTS/ViaPath)

St Thomas' Hospital, London (GSTS/ViaPath)

UCH, London

Viapath, London

Manchester Royal Infirmary