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Cyclic Citrullinated Peptide Antibodies


Cyclic Citrullinated Peptide Antibodies
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Reference Range:

Negative <7 U/ml
Borderline 7 - 10 U/ml
Positive >10 U/ml

Turnaround Time:

3 working days


Internal Test Code:- CCP


Indication: Rheumatoid arthritis

Background: Anti CCP antibodies are targeted against citrullinated peptides and are highly specific for rheumatoid arthritis (RA). They are useful in the early diagnosis of RA and their presence is associated with significantly higher levels of erosions and act as an independent predictor of radiological damage and disease progression.

Method: Fluorescence enzyme immunoassay (FEIA)

Repeat Frequency: As clinically indicated.
Test will not be performed if repeated within 7 days of previous request.



Vessels and Containers:

Serum gold-top

Sample Requirements:

300 µl serum


Lipaemic, haemolysed or microbially contaminated samples may give poor results. Avoid repeat freezing/thawing of samples.

How result is reported:

Numeric in U/ml

Important Information:

Entry Last Modified 22/05/2019



Transportation and Handling:

At room temperature

Special Precautions:


Time limits for requesting additional examinations:

Sample available in this laboratory for approximately 2 weeks. Test can only be added to samples already received by Immunology.