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Glomerular Basement Membrane (GBM) Antibodies

Container:

Glomerular Basement Membrane (GBM) Antibodies
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Reference Range:

< 7 U/ml = Negative
7 - 10 U/ml = Borderline
>10 U/ml = Positive

Turnaround Time:

3 Working Days

Comments:

Internal Test Code:- GBM

Description:

Indication: Rapidly progressing glomerulonephritis

Background: Positive in approximately 90% of Goodpasture’s Syndrome patients. A small number of patients with other renal diseases including systemic vasculitis, SLE and mixed connective tissue disease may exhibit borderline titres.

Method: Fluoresence Enzyme Immunoassay (FEIA)

Repeat Frequency: As clinically indicated and for post treatment monitoring.

Preparation:

None

Vessels and Containers:

Serum gold-top

Sample Requirements:

500µl serum

Interference:

Lipaemic, haemolysed or microbially contaminated samples may give poor results so will not be tested.
Repeated freezing and thawing of samples should be avoided.

How result is reported:

Numeric in U/ml

Important Information:

Please contact laboratory on 01932 723042 for urgent requests.

Entry Last Modified 22/05/2019

Alias:

GBM, GBM Abs, Goodpasture antibodies

Transportation and Handling:

At room temperature

Special Precautions:

None

Time limits for requesting additional examinations:

Sample available in this laboratory for approximately 2 weeks. Test can only be added to samples already received by Immunology.