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Collagen type II antibody

Container:

Collagen type II antibody
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Reference Range:

Negative

Turnaround Time:

10 Working Days

Comments:

Internal Test Code:- CT2

Description:

Indication: Active rheumatoid arthritis and relapsing perichondritis.

Background: Collagens are the major structural proteins of all connective tissues. There are 14 different types of collagen, dependant on the genetic origin and the structural characteristics. Type II collagen belongs to a group of fibrillar collagens that make up the fibrils in most connective tissues. Collagen type II antibodies may be associated with active rhaumatoid arthritis (30-70% of patients) or relapsing perichondritis (60% of patients), however they are of uncertain diagnostic or clinical utility.

Method: Indirect Immunofluorescence (IIF)

Repeat Frequency: As clinically indicated.

Preparation:

None

Vessels and Containers:

Serum gold-top

Sample Requirements:

500µl serum

Interference:

None Known

How result is reported:

Qualitative :- Negative/Positive

Important Information:

Entry Last Modified 22/05/2019

Reference Lab Description:

Protein Reference Unit, Northern General Hospital (Sheffield)

Transportation and Handling:

At room temperature

Special Precautions:

None

Time limits for requesting additional examinations:

Sample available in this laboratory for approximately 2 weeks. Test can only be added to samples already received by Immunology.