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Mannose Binding Lectin (MBL)

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Mannose Binding Lectin (MBL)
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Reference Range:

A tight correlation has been identified between MBL level and genotype.

<75 ng/ml - correlates with homozygous variant alleles and non-functional MBL which is associated with the greatest risk of infection.

75 - 399.9 ng/ml - correlates with functional MBL deficiency associated with increased risk of infection.

400 - 1300 ng/ml correlates with heterozygous variant alleles and may show mild deficiency associated with some increased risk of infection.

>1300 ng/ml correlates with wild type alleles showing no deficiency.

Turnaround Time:

26 working days

Comments:

Internal Test Code:- MBL

Description:

Indication: Recurrent infection

Background: Mannose binding lectin deficiency

Method: Enzyme Linked Immunosorbent Assay (ELISA)

Repeat Frequency: Not required

Preparation:

None

Vessels and Containers:

Serum gold-top

Sample Requirements:

500µl serum

Interference:

None known

How result is reported:

Numeric in ng/ml with interpretive comment.

Important Information:

Entry Last Modified 09/07/2019

Alias:

MBL

Reference Lab Description:

Great Ormond Street Hospital (London)

Transportation and Handling:

At room temperature

Special Precautions:

None

Time limits for requesting additional examinations:

Sample available in this laboratory for approximately 2 weeks. Test can only be added to samples already received by Immunology