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Investigations Referred to Other Laboratories

Microbiology Department

Test Sample Required Approx time result back to lab Location
Acanthamoeba - confirmation Contact lens

Fluid

Corneal scrape
7 days London School of Hygiene and Tropical medicine
Amoebic PCR Faeces 10 days Hospital for Tropical Diseases
Anaerobes Bacterial growth 14 days Anaerobe Reference Laboratory, Cardiff
Bacillus anthracis PCR Tissue biopsy

post-mortem tissue

Culture

Lesion washings
3 days Rare and imported pathogens, Porton Down
Beta-D-glucan Gold top serum 3 days Mycology Reference Laboratory, Bristol
Borrelia burgdoferi PCR (Lyme) Joint fluid

Biopsy

CSF
7 days Rare and imported pathogens, Porton Down
Burkholderia cepacia - typing and antimicrobial resistance Culture 15 days PHE Colindale
Burkholderia mallei/pseudomallei PCR Tissue

Pus/discharge

Culture
Developmental assay - no TAT given Rare and imported pathogens, Porton Down
Brucella spp PCR Tissue

Legion washings
10 days Animal and Plant Health Agency
Campylobacter spp - Identification Culture 14 days PHE Colindale
Clostridium difficile ribotyping Faeces 14 days Leeds Teaching Hospital
Coxiella burnetti PCR Tissue

Heart valve
7 days Rare and imported pathogens, Porton Down
Corynebacterium diptheriae - ID and toxin testing PCR Culture 24 hours PHE Colindale
Cryptococcus antigen PCR CSF

Tissue
1 day Mycology Reference Laboratory, Bristol
E.coli (O:157) - Typing Culture 15 days PHE Colindale
Francisella tularensis PCR Tissue

Wound swab

Culture
5 days Rare and imported pathogens, Porton Down
Fungi - Identification and sensitivity testing Culture 10 days Mycology Reference Laboratory, Bristol
Giardia lamblia PCR Tissue 10 days Hospital for Tropical Diseases
Helicobacter pylori PCR Gastric biopsy in saline 19 days PHE Colindale
Listeria spp PCR CSF 1 day Micropathology LTD
Legionella spp PCR Urine

Respiratory samples

Culture
8 days PHE Colindale
Leptospira spp PCR Urine 3 days Rare and imported pathogens, Porton Down
Meningococcal PCR CSF 1 day Meningococcal Reference Unit, Manchester
Mycobacterium spp - identification and sensitivity testing Positive growth/liquid culture

7 days PHE National Mycobacterium Reference Services
Mycobacterium fast track PCR Primary sample

1 day PHE National Mycobacterium Reference Services
Mycobacterium chimaera culture Blood - lithium heparin tube 6 weeks St George's hospital
Mycoplasma genitalium PCR Urine

Genital swab
2 days Micropathology LTD
Mycoplasma hominis PCR Respiratory sample

CSF

Joint fluid
PCR - 5 days



Culture - 42 days
PHE Colindale
Mycoplasma pneumoniae PCR Respiratory sample

CSF
5 days PHE Colindale
Neisseria gonorrhoea - confirmation of identification Culture 7 days PHE Colindale
Neisseria meningitidis - Identification & typing Fluid

Tissue sample

Culture
2 days Meningococcal Reference Unit, Manchester
Ova / cysts - identification Faeces 6 days London School of Hygiene and Tropical medicine
Parasites - identification Bugs/Ectoparasites 6 days London School of Hygiene and Tropical medicine
PCP PCR BAL

Sputum
2 days Micropathology LTD
PVL (Panton Valentine Leukocidin) Culture 14 days Royal Surrey Foundation Trust
Rickettsia spp PCR CSF 3 days  
Salmonella spp - Identification & typing Culture 17 days PHE Colindale
Shigella spp - Identification and typing Culture 14 days PHE Colindale
Ureaplasma spp PCR Respiratory sample

CSF

Joint fluid
PCR - 5 days



Culture - 42 days
PHE Colindale
Ureaplasma urealyticum/parvum PCR Urine

Genital swab
2 days  Micropathology LTD
VZV/HSV/Enterovirus PCR CSF 2 days Virology Department, St Peters Hospital
16s PCR Various 7 days Great Ormond Street Hospital

 VIROLOGY      
       
       

Test

Samples required

Approx time for result back to lab

Location

Alphavirus

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

Adenovirus PCR

4 mls EDTA

2 days

Micropathology

Amoebic Serology

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Arbovirus

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

Arthropod borne viruses

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

Schistosomiasis

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Brucella

4 mls clotted blood

10 days

Brucella Reference Laboratory (Liverpool)

Camplylobacter serology

4 mls clotted blood

10 days

Specialist Virology Unit Preston

Chikungunya

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

Chlamydia serology (Infertility)

4 mls clotted blood

10 days

HPA South West Bristol

CMV serology*

4 mls clotted blood

2 weeks

Virology Department Royal Free Hospital London

CMV PCR

4 mls EDTA blood / urine / Tissue

2 days

Micropathology

Coxiella*

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

Cryptococcal Ag

4 mls clotted blood

10 days

Mycology Reference Unit (Leeds)

Dengue Fever

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

Fasciola

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Filaria

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Flavivirus

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

Galactomannan

4 mls clotted blood

10 days

HPA South West

Herpes 6&7

4 mls clotted blood / CSF

10 days

HPA East of England (Cambridge)

HSV antibodies

4 mls clotted blood

10 days

London South Specialist Virologist Centre (Kings)

Hydatid

4 mls clotted blood

15 days

HPA Parisitology Reference Laboratory (UCL)

Leishmaniasis

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Leptospira

4 mls clotted blood

10 days

Leptospira Reference Unit (Hereford)

Measles IgM

4 mls clotted blood

10 days

HPA Virus Reference Department (Colindale)

Meningococcus PCR

CSF / 4 mls clotted blood

10 days**

Meningococcal Reference Unit (Manchester) 

Mumps IgM

4 mls clotted blood

10 days

HPA Virus Reference Department (Colindale)

Pneumococcal PCR

CSF / 4 mls clotted blood

10 days**

Meningococcal Reference Unit (Manchester)

Psittacosis*

14 mls clotted blood

10 days

HPA South West (Bristol)

Rabies

4 mls clotted blood

1 month

Veterinary Lab Addlestone

Rickettsia

4 mls clotted blood

10 days

Special Pathogens Reference Unit (Porton Down)

Schistosoma

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Strongyloides

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Teicoplanin Level

4 mls clotted blood

24 hours

Bristol Antimicrobial Laboratory

(telephoned report)

Toxocara

4 mls clotted blood

10 days

HPA Parisitology Reference Laboratory (UCL)

Toxoplasma confirmatory serology*

4 mls clotted blood

10 days

Toxoplasma Reference Laboratory (Swansea)

West Nile

4 mls clotted blood

10 days

Special Pathogens Unit (Porton Down)

 ZIKA ( FULL clinical details and travel history required)

 4 mls clotted blood, EDTA & Urine

 10 days

 Special Pathogens Unit (Porton Down)

* Those tests marked with asterix are carried out at St Peter's Hospital before referral.

** A positive result will be telephoned as soon as the reference lab have informed the department of the result

OTHER TESTS MAY BE AVAILABLE, PLEASE CONTACT THE LABORATORY TO DISCUSS.

 

Functional antibody tests performed in Immunology

  • Pneumococcal antibodies
  • Tetanus antibodies
  • Haemophilus influenzae antibodies
  • Aspergillus Precipitins